SCHEMBL10135233

SCHEMBL10135233

CCC(c1ccccc1)c1nc2cc(C(=O)O)ccc2c2sccc12

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 20/20 0.57
CSNK2A2 P19784 2/20 0.52
CSNK2B P67870 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10132462 0.75 CSNK2A1 (0.74) CSNK2A1CSNK2A2CSNK2B
SCHEMBL1930159 0.73 CSNK2A1 (0.65) CSNK2A1CSNK2A2CSNK2B
SCHEMBL10132445 0.73 CSNK2A1 (1.00) CSNK2A1CSNK2A2CSNK2B
SCHEMBL1930065 0.72 CSNK2A1 (1.00) CSNK2A1
SCHEMBL10132454 0.70 CSNK2A1 (1.00) CSNK2A1
SCHEMBL10132438 0.70 CSNK2A1 (1.00) CSNK2A1CSNK2A2CSNK2B
SCHEMBL2689471 0.70 CSNK2A1 (1.00) CSNK2A1CSNK2A2CSNK2B
SCHEMBL10132434 0.70 CSNK2A1 (0.77) CSNK2A1CSNK2A2CSNK2B
SCHEMBL10132535 0.70 CSNK2A1 (1.00) CSNK2A1
SCHEMBL10132372 0.69 CSNK2A1 (1.00) CSNK2A1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168651-B2 Protein kinase modulators CYLENE PHARMACEUTICALS, INC. (US) 2012-05-01 US disclosed
US-8168651-B2 Protein kinase modulators CYLENE PHARMACEUTICALS, INC. (US) 2012-05-01 US disclosed