Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781589 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL29283281 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL29009042 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL28536719 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL5246994 | 1.00 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL24835739 | 0.89 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL31591142 | 0.89 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL30552236 | 0.89 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL22326177 | 0.89 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1CHRM2 | |
| SCHEMBL22326195 | 0.89 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011514423-A | — | — | 2011-05-06 | — | — | JP | claimed |
| EP-2271699-A1 | BIODEGRADABLE CROSS-LINKED BRANCHED POLY (ALKYLENE IMINES) | Egen, Inc. (US) | 2011-01-12 | — | — | EP | claimed |
| WO-2009114854-A1 | BIODEGRADABLE CROSS-LINKED BRANCHED POLY (ALKYLENE IMINES) | EGEN, INC. (US) | 2009-09-17 | — | — | WO | claimed |
| EP-2271699-A1 | BIODEGRADABLE CROSS-LINKED BRANCHED POLY (ALKYLENE IMINES) | Egen, Inc. (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009114854-A1 | BIODEGRADABLE CROSS-LINKED BRANCHED POLY (ALKYLENE IMINES) | EGEN, INC. (US) | 2009-09-17 | — | — | WO | disclosed |