Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 5/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024848 | 0.89 | PARP15 (0.64) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL16902834 | 0.78 | PARP15 (0.59) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL9966867 | 0.78 | PARP15 (0.55) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL255654 | 0.78 | PARP15 (0.55) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL8930160 | 0.78 | PARP15 (0.55) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL24180195 | 0.78 | PARP15 (0.55) | PARP15PARP10PARP2SIGMAR1 | |
| SCHEMBL3667235 | 0.78 | PARP15 (0.55) | PARP15PARP10PARP2TDP1 | |
| SCHEMBL13135282 | 0.78 | HPGD (0.57) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL16838742 | 0.78 | TDP1 (0.73) | PARP15PARP10PARP2TDP1SIGMAR1 | |
| SCHEMBL2665020 | 0.78 | PARP15 (0.55) | PARP15PARP10PARP2TDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032014-A1 | ETHYNE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-15 | — | — | WO | disclosed |