Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.70 |
| ▸ | CNR2 | P34972 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053795 | 0.93 | CNR1 (0.70) | CNR1CNR2 | |
| SCHEMBL12053720 | 0.91 | CNR1 (0.67) | CNR1CNR2 | |
| SCHEMBL10170798 | 0.89 | CNR1 (0.65) | CNR1CNR2 | |
| SCHEMBL12053799 | 0.85 | CNR1 (0.71) | CNR1CNR2 | |
| SCHEMBL10139074 | 0.85 | CNR1 (0.71) | CNR1CNR2KCNH2 | |
| SCHEMBL12053809 | 0.84 | CNR1 (0.69) | CNR1CNR2 | |
| SCHEMBL12053970 | 0.83 | CNR1 (0.85) | CNR1CNR2KCNH2 | |
| SCHEMBL12053793 | 0.81 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL3999243 | 0.81 | CNR1 (0.70) | CNR1CNR2KCNH2 | |
| SCHEMBL2873286 | 0.81 | CNR1 (0.70) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853205-B2 | Heteropyrrole analogs acting on cannabinoid receptors | UNIVERSITY OF CONNECTICUT (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | UNIVERSITY OF CONNECTICUT | 2012-02-23 | — | — | US | disclosed |
| US-8084467-B2 | For both CB1 and CB2 receptor sites; 3-(N-hetero)amido-5-phenyl pyrazoles; memory deficits associated with aging or nervous system disorders, obesity, schizophrenia, septic shock | UNIVERSITY OF CONNECTICUT (US) | 2011-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046280-A1 | NOVEL HETEROPYRROLE ANALOGS ACTING ON CANNABINOID RECEPTORS | CNR1, CNR2, CBR3 | CNR1 1/4885CNR2 2/4885KCNH2 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.