SCHEMBL1013946

SCHEMBL1013946

[Rh].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.92
CYP3A4 P08684 1/20 0.92
ESR1 P03372 4/20 0.63
ESR2 Q92731 4/20 0.63
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
ALDH1A1 P00352 4/20 0.38
NPSR1 Q6W5P4 1/20 0.37
DRD1 P21728 2/20 0.35
TSHR P16473 4/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375622 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL19097318 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL788643 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL10565176 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL9169400 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL1982595 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL852493 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL10276789 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL6320882 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL7202751 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114849787-A Aryl bidentate phosphine ligand polymer in-situ encapsulation rhodium-based catalytic material and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-08-05 CN claimed
CN-110540608-A Method for preparing hydrogenated diene based nanoemulsions and use of gemini surfactants WANG HUI 2019-12-06 CN claimed
EP-2072538-B1 Hydrogenation of diene-based polymer latex LANXESS INC (CA) 2014-02-26 EP claimed
EP-1862477-B1 Process for preparing hydrogenated nitrile rubbers LANXESS DEUTSCHLAND GMBH (DE) 2013-03-06 EP claimed
EP-2151455-B1 Process for the continuous hydrogenation of carbon-carbon double bonds in an unsaturated polymer LANXESS INC (CA) 2012-11-14 EP claimed
EP-2147933-B1 Process for the continuous hydrogenation of carbon-carbon double bonds in an unsaturated polymer to produce a hydrogenated polymer LANXESS INC (CA) 2012-10-31 EP claimed
EP-1705194-B1 Hydrogenation of diene-based polymer latex LANXESS INC (CA) 2011-01-05 EP claimed
EP-1702930-B1 Organic solvent-free hydrogenation of diene-based polymers LANXESS INC (CA) 2010-10-20 EP claimed
EP-0321174-B1 Process for preparing aminopropyl silanes TONEN CORP (JP) 1994-03-23 EP claimed
CN-112654630-B Tetradentate diaminodiphosphine ligands, transition metal complexes, methods for their production and use thereof 高砂香料工业株式会社 2024-05-24 CN disclosed
CN-114849787-B Aryl bidentate phosphine ligand polymer in-situ encapsulation rhodium-based catalytic material and preparation method and application thereof 中国科学院兰州化学物理研究所 2023-07-28 CN disclosed
CN-110540608-B Method for preparing hydrogenated diene based nanoemulsions and use of gemini surfactants 王辉 2022-12-23 CN disclosed
CN-114849787-A Aryl bidentate phosphine ligand polymer in-situ encapsulation rhodium-based catalytic material and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-08-05 CN disclosed
CN-113522366-B Monophosphine-containing porous organic polymer in-situ packaging rhodium catalytic material, and preparation method and application thereof 中国科学院兰州化学物理研究所 2022-08-02 CN disclosed
US-5068275-A Resistance to hot air aging POLYSAR RUBBER CORPORATION (CA) 1991-11-26 US disclosed
EP-0444616-A1 Sulfenyl chloride adducts of hydrogenated nitrile rubber BAYER RUBBER INC. (CA) 1991-09-04 EP disclosed
US-5043394-A Vulcanized seals, gaskets NOVA PETROCHEMICALS INC. (CA) 1991-08-27 US disclosed
EP-0440180-A1 Plasticized hydrogenated nitrile rubber POLYSAR RUBBER CORPORATION (CA) 1991-08-07 EP disclosed
US-5019419-A Polysiloxane TOSHIBA SILICONE CO. LTD. (JP) 1991-05-28 US disclosed
US-4721750-A Primer composition TOSHIBA SILICONE COMPANY, LTD. (JP) 1988-01-26 US disclosed