⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114388 | 1.00 | TSHR (0.57) | — | |
| SCHEMBL28298 | 1.00 | — | — | |
| SCHEMBL10141202 | 1.00 | — | — | |
| Phosphine SCHEMBL30485793 | 0.97 | — | — | |
| SCHEMBL17363100 | 0.97 | — | — | |
| SCHEMBL27916020 | 0.97 | — | — | |
| SCHEMBL4325727 | 0.97 | — | — | |
| Water SCHEMBL5567597 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1147719 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28091123 | 0.97 | TSHR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 914 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160205-B | Method for preparing (S) -1- (tert-butoxycarbonyl) -2, 5-dihydro-1H-pyrrole-2-carboxylic acid and salt thereof | 上海皓鸿生物医药科技有限公司 | 2024-06-07 | — | — | CN | claimed |
| WO-2024063670-A1 | CYCLIN-DEPENDENT KINASE 7 INHIBITORS | Акционерное общество "БИОКАД" | 2024-03-28 | — | — | WO | claimed |
| WO-2023072104-A1 | METAL-ORGANIC FRAMEWORK MATERIAL AND PREPARATION METHOD THEREFOR | 广东美的白色家电技术创新中心有限公司 | 2023-05-04 | — | — | WO | claimed |
| CN-115925606-A | 5- (3- (sulfonamido) phenyl) -1H-pyrrole-2-carboxylic acid derivative and preparation method and application thereof | 宁夏医科大学 | 2023-04-07 | — | — | CN | claimed |
| EP-4130008-A1 | NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND PREPARATION METHOD THEREFOR | J&C Sciences (KR) | 2023-02-08 | — | — | EP | claimed |
| US-20230011441-A1 | PYRAZOLO[3,4-b]PYRIDINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES | ARRAY BIOPHARMA INC. (US) | 2023-01-12 | — | — | US | claimed |
| CN-115160205-A | Method for preparing (S) -1- (tert-butyloxycarbonyl) -2, 5-dihydro-1H-pyrrole-2-carboxylic acid and salt thereof | 上海皓鸿生物医药科技有限公司 | 2022-10-11 | — | — | CN | claimed |
| CN-114044913-A | Metal-organic framework material and preparation method thereof | 广东美的白色家电技术创新中心有限公司 | 2022-02-15 | — | — | CN | claimed |
| CN-113993846-A | Compositions and methods for treating pain and/or inflammation | 诺门图姆股份有限公司 | 2022-01-28 | — | — | CN | claimed |
| US-20210347783-A1 | NOVEL DERIVATIVE OF BETA-APOPICROPODOPHYLLIN AND METHOD OF PREPARING THEREOF | J&C SCIENCES (KR) | 2021-11-11 | — | — | US | claimed |
| US-20100292207-A1 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2010-11-18 | — | — | US | claimed |
| US-7718692-B2 | or antipyretics; use of N-heterocyclecarboxylic acid, p-hydroxyphenyl amides or N-(p-hydroxyphenyl)-2-thio-group substituted acetamides; e.g. Pyrrolidine-2-carboxylic acid (p-hydroxyphenyl)-amide; substitute for aspirin in upper GI disease, aspirin allergy, bleeding disorders, clients on anticoagulants | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-05-18 | — | — | US | claimed |
| US-7638550-B2 | new compounds derived from formula I pyrroles, methods for obtaining them and their application as drugs in pharmaceutical compositions for the treatment of cancer due to their inhibitory activity on certain histone deacetylases. | Universidad del Pais Vasco-Euskal Herriko Unibertsitatea (UPV-EHU) Fundacion Centro Nacional de Investigaciones Oncologicas Carlos III (CNIO) (ES) | 2009-12-29 | — | — | US | claimed |
| US-20090023741-A1 | ARYL/HETARYLAMIDES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AG (DE) | 2009-01-22 | — | — | US | claimed |
| US-20080318950-A1 | Quinazoline Derivatives as a Multiplex Inhibitor and Method For the Preparation Thereof | HANMI PHARM. CO., LTD (KR) | 2008-12-25 | — | — | US | claimed |
| US-20080262073-A1 | Pyrrolic Derivatives with Histone Deacetylase Inhibitory Activity | FUNDACION CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III (CNIO) (ES) | 2008-10-23 | — | — | US | claimed |
| US-20060149066-A1 | Imidazole derivatives | PFIZER INC | 2006-07-06 | — | — | US | claimed |
| US-20050038248-A1 | Chemotherapeutic agents | STARPHARMA PTY LTD (AU) | 2005-02-17 | — | — | US | claimed |
| CN-1447794-A | Novel compounds | ASTRAZENECA AB (SE) | 2003-10-08 | — | — | CN | claimed |
| US-20020119963-A1 | Imidazole derivatives | PFIZER PRODUCTS INC. | 2002-08-29 | — | — | US | claimed |