SCHEMBL10141353

SCHEMBL10141353

CCOc1ccc2nc(NC(=O)C(OC3CCCCC3)c3ccc([S+]([O-])C4CCOCC4)cc3)sc2n1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GCK P35557 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL625463 0.86 GCK (0.68) GCK
SCHEMBL184261 0.82 GCK (0.75) GCK
SCHEMBL625064 0.76 GCK (0.57) GCK
SCHEMBL185138 0.76 GCK (0.67) GCK
SCHEMBL623375 0.75 GCK (0.57) GCK
SCHEMBL624329 0.74 GCK (0.60) GCK
SCHEMBL186092 0.74 GCK (0.71) GCK
SCHEMBL185097 0.73 GCK (0.79) GCK
SCHEMBL184720 0.73 GCK (0.91) GCK
SCHEMBL11972305 0.72 GCK (0.66) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020357-A1 ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION ADVINUS THERAPEUTICS LTD. (IN) 2012-02-16 WO disclosed