Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.62 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142576 | 0.90 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1FFAR4FFAR1 | |
| SCHEMBL10141541 | 0.87 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1FFAR4FFAR1 | |
| SCHEMBL12074001 | 0.86 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1FFAR4FFAR1 | |
| SCHEMBL10120784 | 0.85 | CYSLTR2 (0.82) | CYSLTR2CYSLTR1 | |
| SCHEMBL10143243 | 0.85 | CYSLTR2 (0.76) | CYSLTR2CYSLTR1 | |
| SCHEMBL597067 | 0.81 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1 | |
| SCHEMBL598421 | 0.78 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1 | |
| SCHEMBL12073949 | 0.78 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1 | |
| SCHEMBL598114 | 0.77 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1 | |
| SCHEMBL598115 | 0.77 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115014-B2 | Ethynylindole compounds | ONO Pharmaceuticals, Co., Ltd. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100160647-A1 | ETHYNYLINDOLE COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160647-A1 | ETHYNYLINDOLE COMPOUNDS | CYSLTR2, CYSLTR1, LTB4R2 | CYSLTR2 1/4885CYSLTR1 2/4885FFAR4 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.