Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | BTN3A1 | O00481 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142317 | 1.00 | CYP3A4 (0.37) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL15257115 | 0.96 | CYP3A4 (0.42) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142322 | 0.96 | CYP3A4 (0.37) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142329 | 0.96 | CYP3A4 (0.37) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142330 | 0.93 | CYP3A4 (0.35) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142340 | 0.93 | CYP3A4 (0.35) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142339 | 0.93 | CYP3A4 (0.35) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142918 | 0.93 | CYP3A4 (0.35) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142377 | 0.92 | CYP3A4 (0.41) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL10142738 | 0.91 | BTN3A1 (0.36) | CYP3A4CYP2C9BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415308-B2 | 1′-substituted-carba-nucleoside prodrugs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120020921-A1 | 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020921-A1 | 1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT | PNP, TYMP, MTAP | CYP3A4 373/4885CYP2C9 1163/4885BTN3A1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.