Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514478 | 0.89 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL18403815 | 0.88 | PTGDR2 (0.79) | PTGDR2 | |
| SCHEMBL10142626 | 0.86 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL10142519 | 0.81 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL8513144 | 0.81 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL8514266 | 0.79 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL15747224 | 0.79 | PTGDR2 (0.79) | PTGDR2 | |
| SCHEMBL10142724 | 0.78 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL10142931 | 0.78 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL10142774 | 0.77 | PTGDR2 (1.00) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528901-B9 | PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2017-01-25 | — | — | EP | disclosed |
| EP-2528901-B1 | PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2015-05-27 | — | — | EP | disclosed |
| US-8791272-B2 | Pyrazole compounds as CRTH2 antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| US-8791272-B2 | Pyrazole compounds as CRTH2 antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-07-29 | — | — | US | disclosed |
| WO-2014079805-A1 | PYRAZOLE COMPOUNDS FOR TREATING HAIRLOSS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-30 | — | — | WO | disclosed |
| US-20140148484-A1 | PYRAZOLE COMPOUNDS FOR TREATING HAIRLOSS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20140148484-A1 | PYRAZOLE COMPOUNDS FOR TREATING HAIRLOSS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20120028938-A1 | PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| US-20120028938-A1 | PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028938-A1 | PYRAZOLE COMPOUNDS AS CRTH2 ANTAGONISTS | HRH2, HRH1, HRH3 | PTGDR2 29/4885 |
| US-20140148484-A1 | PYRAZOLE COMPOUNDS FOR TREATING HAIRLOSS | SUCLG1, TYR, CYP2S1 | PTGDR2 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.