Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.88 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143210 | 1.00 | PPARD (0.88) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL659025 | 1.00 | PPARD (0.88) | PPARDPPARAPPARGPTGDR2 | |
| SCHEMBL3269098 | 0.95 | PPARD (0.94) | PPARDPPARAPTGDR2 | |
| SCHEMBL13234246 | 0.95 | PPARD (0.94) | PPARDPPARAPTGDR2 | |
| SCHEMBL3269095 | 0.95 | PPARD (0.94) | PPARDPPARAPTGDR2 | |
| SCHEMBL5959504 | 0.95 | PPARD (0.78) | PPARDPPARAPPARG | |
| SCHEMBL5959547 | 0.95 | PPARD (0.78) | PPARDPPARAPPARG | |
| SCHEMBL12159944 | 0.94 | PPARD (0.77) | PPARDPPARAPPARG | |
| SCHEMBL657073 | 0.94 | PPARD (1.00) | PPARDPPARAPTGDR2 | |
| SCHEMBL657912 | 0.92 | PPARD (0.85) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046350-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS, LLC (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046350-A1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | PPARG, PPARD, PPARA | PPARD 2/4885PPARA 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.