Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366088 | 0.88 | CHEK1 (0.44) | TERTCHEK1LTA4HKDM4EALDH1A1 | |
| SCHEMBL10143785 | 0.82 | CA1 (0.45) | CHEK1KDM4EGLAGAAKMT2A | |
| SCHEMBL10144322 | 0.82 | CA1 (0.45) | CHEK1KDM4EGLAGAAKMT2A | |
| SCHEMBL29543976 | 0.79 | CA12 (0.58) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL29355291 | 0.79 | CA12 (0.58) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL5664318 | 0.79 | CA12 (0.58) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL7203173 | 0.79 | CA12 (0.58) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL14369937 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HPGDGLAGAA | |
| Acetic Acid SCHEMBL29576439 | 0.77 | CA12 (0.58) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL12330807 | 0.76 | KDM4E (0.44) | TERTCHEK1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |