Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144196 | 0.91 | TLR2 (0.43) | TLR2PTPN1ITGB3ITGA2BMMP3 | |
| SCHEMBL10143498 | 0.90 | MDM2 (0.41) | — | |
| SCHEMBL10143497 | 0.89 | TLR2 (0.42) | TLR2PTPN1HDAC1HDAC2 | |
| SCHEMBL10143502 | 0.89 | TLR2 (0.45) | TLR2PTPN1MMP3HDAC4 | |
| SCHEMBL10143499 | 0.88 | TLR2 (0.45) | TLR2PTPN1HDAC4 | |
| SCHEMBL10144445 | 0.87 | TLR2 (0.46) | TLR2PTPN1DPP8 | |
| SCHEMBL10144324 | 0.86 | TLR2 (0.44) | TLR2PTPN1HDAC4 | |
| SCHEMBL10143538 | 0.85 | TLR2 (0.54) | TLR2PTPN1MMP3HDAC1HDAC2 | |
| SCHEMBL10144428 | 0.85 | TLR2 (0.42) | TLR2PTPN1HDAC4 | |
| SCHEMBL10144408 | 0.85 | TLR2 (0.47) | TLR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |