Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 15/20 | 0.82 |
| ▸ | GALR1 | P47211 | 5/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143469 | 0.96 | GALR2 (0.82) | GALR2GALR1AURKACTSLCTSB | |
| SCHEMBL10143391 | 0.91 | GALR2 (1.00) | GALR2GALR1AURKA | |
| SCHEMBL10143662 | 0.85 | GALR2 (0.82) | GALR2GALR1AURKA | |
| SCHEMBL10143487 | 0.85 | GALR2 (0.82) | GALR2GALR1AURKACTSLCTSB | |
| SCHEMBL10143455 | 0.84 | GALR2 (0.80) | GALR2GALR1AURKA | |
| SCHEMBL10143474 | 0.84 | GALR2 (0.86) | GALR2GALR1AURKA | |
| SCHEMBL10143741 | 0.83 | GALR2 (0.79) | GALR2GALR1AURKA | |
| SCHEMBL10143461 | 0.83 | GALR2 (0.78) | GALR2GALR1AURKA | |
| SCHEMBL10143393 | 0.83 | GALR2 (1.00) | GALR2GALR1AURKA | |
| SCHEMBL10143620 | 0.83 | GALR2 (0.78) | GALR2GALR1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |