SCHEMBL10144179

SCHEMBL10144179

COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(N3CCCC3)n2)cc1

nearest known ligand 0.98

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GALR2 O43603 17/20 0.98
GALR1 P47211 8/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10143433 0.99 GALR2 (1.00) GALR2GALR1
SCHEMBL10143601 0.99 GALR2 (1.00) GALR2GALR1
SCHEMBL10143623 0.99 GALR2 (1.00) GALR2GALR1
SCHEMBL10143489 0.92 GALR2 (0.83) GALR2GALR1
SCHEMBL10144327 0.92 GALR1 (1.00) GALR2GALR1
SCHEMBL10143491 0.91 GALR2 (0.82) GALR2GALR1
SCHEMBL10143747 0.90 GALR2 (0.84) GALR2GALR1
SCHEMBL10143615 0.90 GALR2 (0.84) GALR2GALR1
SCHEMBL10143780 0.90 GALR2 (0.84) GALR2GALR1
SCHEMBL10143446 0.90 GALR2 (0.84) GALR2GALR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012009258-A2 PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS ROBERTS EDWARD (US) 2012-01-19 WO disclosed