Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 4/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Galnon SCHEMBL6834012 | 0.90 | TLR2 (0.44) | SLC17A5TLR2KDM4EALDH1A1SMN1; SMN2 | |
| Galnon SCHEMBL4464884 | 0.90 | TLR2 (0.44) | SLC17A5TLR2KDM4EALDH1A1SMN1; SMN2 | |
| Galnon SCHEMBL29711017 | 0.90 | TLR2 (0.44) | SLC17A5TLR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10144194 | 0.89 | MDM2 (0.39) | CA1MDM2CA2TLR2TLR1 | |
| SCHEMBL10144113 | 0.88 | MDM2 (0.41) | CA1MDM2CA2TLR2TLR1 | |
| SCHEMBL10144210 | 0.87 | MDM2 (0.40) | CA1MDM2CA2TLR2TLR1 | |
| SCHEMBL10143778 | 0.87 | MDM2 (0.41) | CA1MDM2CA2TLR2TLR1 | |
| SCHEMBL10144157 | 0.87 | MDM2 (0.40) | CA1MDM2CA2TLR2TLR1 | |
| SCHEMBL10144131 | 0.87 | MDM2 (0.41) | CA1MDM2CA2TLR2TLR1 | |
| SCHEMBL10144410 | 0.86 | MDM2 (0.41) | CA1MDM2CA2TLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |