Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116603 | 0.90 | GRM5 (0.77) | GRM5L3MBTL1KMT2AMEN1SMYD3 | |
| SCHEMBL23573558 | 0.84 | GRM5 (0.69) | GRM5L3MBTL1KMT2AMEN1CCR3 | |
| SCHEMBL15962709 | 0.84 | GRM5 (0.69) | GRM5L3MBTL1KMT2AMEN1SMYD3 | |
| SCHEMBL23573560 | 0.84 | GRM5 (0.69) | GRM5L3MBTL1KMT2AMEN1CCR3 | |
| SCHEMBL3462086 | 0.82 | GRM5 (0.71) | GRM5L3MBTL1KMT2AMEN1CCR3 | |
| SCHEMBL13294374 | 0.82 | GRM5 (0.81) | GRM5L3MBTL1KMT2AMEN1HTR2B | |
| SCHEMBL12259124 | 0.82 | GRM5 (0.66) | GRM5L3MBTL1KMT2AMEN1CCR3 | |
| SCHEMBL4403625 | 0.80 | GRM5 (0.68) | GRM5L3MBTL1KMT2AMEN1SMYD3 | |
| SCHEMBL29639471 | 0.80 | GRM5 (0.68) | GRM5L3MBTL1KMT2AMEN1CCR3 | |
| SCHEMBL29973192 | 0.78 | KMT2A (0.65) | GRM5L3MBTL1KMT2AMEN1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404896-A1 | CYCLOHEXANE DERIVATIVE HAVING NPY Y5 RECEPTOR ANTAGONISM | Shionogi&Co., Ltd. (JP) | 2012-01-11 | — | — | EP | disclosed |