Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145605 | 0.89 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL610032 | 0.87 | HCRTR2 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL10145342 | 0.84 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL9897251 | 0.77 | HCRTR2 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL610025 | 0.76 | HCRTR2 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL610535 | 0.76 | HCRTR2 (0.61) | HCRTR1HCRTR2 | |
| SCHEMBL16039061 | 0.75 | HCRTR2 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL295417 | 0.75 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL9899193 | 0.72 | HCRTR2 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL10144794 | 0.72 | ALOX5AP (0.40) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | HCRTR2, HCRTR1, NPY2R | HCRTR1 2/4885HCRTR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.