Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144933 | 0.90 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL7862854 | 0.88 | HCRTR2 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL611060 | 0.88 | HCRTR2 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL10121671 | 0.88 | HCRTR2 (0.64) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL609560 | 0.88 | HCRTR2 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL9896979 | 0.85 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL609382 | 0.83 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL706969 | 0.83 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL609050 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL21891394 | 0.80 | HCRTR2 (0.62) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040991-A1 | 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS | HCRTR2, HCRTR1, NPY2R | HCRTR1 2/4885HCRTR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.