Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679999 | 0.94 | MCHR1 (0.78) | MCHR1CYP3A4CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL539150 | 0.94 | MCHR1 (0.77) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL10144494 | 0.92 | MCHR1 (0.83) | MCHR1CYP3A4CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL539097 | 0.91 | MCHR1 (0.81) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL12680001 | 0.90 | MCHR1 (0.78) | MCHR1CYP3A4CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL539110 | 0.89 | MCHR1 (0.77) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL10145070 | 0.89 | MCHR1 (0.78) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL10144518 | 0.89 | MCHR1 (1.00) | MCHR1CYP3A4CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL538999 | 0.88 | MCHR1 (0.77) | MCHR1CYP3A4CYP2C19KCNH2 | |
| SCHEMBL12680234 | 0.88 | MCHR1 (0.81) | MCHR1CYP3A4CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176251-B1 | 5-pyridinone substituted indazoles and pharmaceutical compositions thereof | ALBANY MOLECULAR RES INC (US) | 2012-02-08 | — | — | EP | disclosed |