SCHEMBL10145377

SCHEMBL10145377

C=CC[C@H](N)CC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL174163 0.85
Bromide SCHEMBL28609992 0.82
Hydrochloric Acid SCHEMBL547389 0.82
SCHEMBL30978336 0.82
Sulfur Dioxide SCHEMBL28907029 0.78 GRIK1 (0.35)
Chloromethane SCHEMBL27813211 0.77 GRIK1 (0.33)
Phosphoric Acid SCHEMBL5172101 0.76 GRIK1 (0.39)
Sulfuric Acid SCHEMBL5169847 0.76 GRIK1 (0.39)
Phosphoric Acid SCHEMBL7159378 0.76 GRIK1 (0.39)
Sulfuric Acid SCHEMBL28879549 0.76 GRIK1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120040991-A1 3-AZABICYCLO [4.1.0] HEPTANES USED AS OREXIN ANTAGONISTS GLAXO GROUP LIMITED (GB) 2012-02-16 US disclosed