Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145706 | 0.93 | MAPT (0.43) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145698 | 0.91 | MAPT (0.43) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145602 | 0.84 | MAPT (0.43) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL13648698 | 0.84 | MAPT (0.43) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145608 | 0.83 | MAPT (0.49) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145537 | 0.83 | MAPT (0.41) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145610 | 0.82 | MEN1 (0.46) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145589 | 0.80 | CYP3A4 (0.40) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145597 | 0.79 | CYP3A4 (0.39) | MAPTLMNAMEN1KMT2AHTT | |
| SCHEMBL10145477 | 0.77 | MAPT (0.52) | MAPTLMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114904-B2 | Luminescence quenchers and fluorogenic probes for detection of reactive species | Versitech Limited & Morningside Ventures Limited (CN) | 2012-02-14 | — | — | US | disclosed |