Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10146309 | 0.82 | MAPK14 (0.43) | MAPK14GAAPOLBRAB9ANPC1 | |
| SCHEMBL351579 | 0.82 | HCAR2 (0.57) | HCAR2MAPK14GAARAB9ANPC1 | |
| SCHEMBL352786 | 0.79 | HCAR2 (0.42) | HCAR2GAAALDH1A1PTPN1CNR2 | |
| SCHEMBL2565757 | 0.74 | HCAR2 (0.52) | HCAR2MAPK14GAAPOLBALDH1A1 | |
| SCHEMBL27876364 | 0.73 | HCAR2 (0.50) | HCAR2MAPK14GAAPOLBALDH1A1 | |
| SCHEMBL10104256 | 0.72 | MAPK14 (0.38) | MAPK14GAARAB9ANPC1ALDH1A1 | |
| SCHEMBL3805132 | 0.71 | CNR2 (0.40) | HCAR2MAPK14POLBALDH1A1CNR2 | |
| SCHEMBL13890431 | 0.71 | MAPK14 (0.37) | MAPK14SMN1; SMN2 | |
| SCHEMBL2676735 | 0.71 | MAPK14 (0.37) | MAPK14RAB9ANPC1ALDH1A1CNR2 | |
| SCHEMBL597064 | 0.71 | HCAR2 (0.57) | HCAR2GAAPOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015988-A1 | Sulfone Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, TRPV1 | HCAR2 51/4885MAPK14 1347/4885GAA 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.