Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992416 | 0.87 | GRM2 (0.46) | GRM2 | |
| SCHEMBL10146662 | 0.83 | GRM2 (0.50) | GRM2PARG | |
| SCHEMBL625980 | 0.80 | GRM2 (0.50) | GRM2PARG | |
| SCHEMBL627481 | 0.78 | GRM2 (0.47) | GRM2PARG | |
| SCHEMBL14992998 | 0.77 | GRM2 (0.49) | GRM2 | |
| SCHEMBL627447 | 0.77 | GRM2 (0.55) | GRM2PARG | |
| SCHEMBL10146378 | 0.77 | GRM2 (0.61) | GRM2PARG | |
| SCHEMBL10145822 | 0.77 | GRM2 (0.49) | GRM2PARG | |
| SCHEMBL10145856 | 0.75 | GRM2 (0.58) | GRM2PARG | |
| SCHEMBL10146383 | 0.73 | GRM2 (0.65) | GRM2PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021382-A1 | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 | MERCK SHARP & DOHME CORP. (US) | 2012-02-16 | — | — | WO | disclosed |