Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657051 | 0.95 | MAOB (0.46) | HSP90AA1MAOBHSP90AB1CYP19A1AKR1C3 | |
| SCHEMBL10147649 | 0.88 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CYP19A1AKR1C3MAPT | |
| SCHEMBL10147481 | 0.86 | HSP90AA1 (0.51) | HSP90AA1MAOBHSP90AB1CYP19A1MAPT | |
| SCHEMBL7898075 | 0.83 | HSP90AA1 (0.44) | HSP90AA1MAOBHSP90AB1MAPTAR | |
| SCHEMBL658319 | 0.83 | HSP90AA1 (0.43) | HSP90AA1MAOBHSP90AB1MAPTMEN1 | |
| SCHEMBL10147497 | 0.82 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1CYP19A1MAPTMEN1 | |
| SCHEMBL656722 | 0.82 | HSP90AA1 (0.53) | HSP90AA1HSP90AB1CYP19A1AKR1C3MAPT | |
| SCHEMBL657005 | 0.82 | HSP90AA1 (0.46) | HSP90AA1MAOBHSP90AB1MAPTMEN1 | |
| SCHEMBL656598 | 0.82 | HSP90AA1 (0.62) | HSP90AA1MAOBHSP90AB1MAPTKDM4E | |
| SCHEMBL656954 | 0.81 | HSP90AA1 (0.51) | HSP90AA1MAOBHSP90AB1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993556-B2 | Resorcinol derivatives as HSP90 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-31 | — | — | US | disclosed |
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885MAOB 3733/4885HSP90AB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.