SCHEMBL1014781

SCHEMBL1014781

O=C(O)C(O)SC(O)C(=O)OC(=O)C(O)SC(O)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41377 0.83 TSHR (0.44) TSHRTP53
SCHEMBL633576 0.80 SMN1; SMN2 (0.37) TP53
Ammonia Solution, Strong SCHEMBL2420015 0.80 TSHR (0.41) TSHRTP53
Ammonia Solution, Strong SCHEMBL246433 0.80 TSHR (0.41) TSHRTP53
Ammonia Solution, Strong SCHEMBL339617 0.80 TSHR (0.41) TSHRTP53
SCHEMBL6045961 0.79 TSHR (0.32) TSHRTP53
Methyl Alcohol SCHEMBL9810522 0.77 TP53 (0.44) TSHRTP53
SCHEMBL23853947 0.75 KMT2A (0.33)
SCHEMBL9769766 0.75 TSHR (0.34) TSHR
SCHEMBL3139582 0.73 HCAR2 (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081040-A Preparation method of chemically recyclable polyacetal and product and chemical recycling method thereof 浙江大学 2024-12-06 CN claimed
CN-118994284-A Gemcitabine prodrug or pharmaceutically acceptable salt thereof containing side chains with different flexibilities, self-assembled nanoparticle thereof and application 沈阳药科大学 2024-11-22 CN claimed
CN-118955886-A Carbonate functionalized polymer and synthetic method and application thereof 华南理工大学 2024-11-15 CN claimed
US-20240368726-A1 THIODIGLYCOLAMIC ACID EXTRACTANT, AND PREPARATION METHOD AND USE THEREOF INSTITUTE OF APPLIED CHEMISTRY, JIANGXI ACADEMY OF SCIENCES (CN) 2024-11-07 US claimed
CN-118702912-A Preparation method of spontaneously degradable cyclic poly (ester-peptide), product and degradation method thereof 浙江大学 2024-09-27 CN claimed
CN-118406203-A Preparation method of intrinsic flame-retardant high-strength polyacetal and product thereof 浙江大学 2024-07-30 CN claimed
CN-118271570-A Preparation method of organic phosphine-terminated non-conjugated oxygen-enriched fluorescent polymer, and product and application thereof 浙江大学 2024-07-02 CN claimed
CN-118184555-A Method for synthesizing and purifying HDEHSDGA 山东第一医科大学(山东省医学科学院) 2024-06-14 CN claimed
CN-117736254-A N, N-dimethyl ethylenediamine-thiodiglycolic acid mono-cholesterol ester conjugate and preparation method and application thereof 常州大学 2024-03-22 CN claimed
CN-114853617-B Extracting agent for extracting and separating neodymium (III), preparation method and application thereof 山东大学 2023-12-22 CN claimed
CN-115028561-B Thiobis Gan Xianan acid extractant, and preparation method and application thereof 江西省科学院应用化学研究所 2023-12-22 CN claimed
CN-116003771-A Synthesis method of alpha, beta-unsaturated carboxylic ester functionalized polymer 华南理工大学 2023-04-25 CN claimed
CN-115536825-A Copolymerization method of anhydride and epoxy catalyzed by fluorine catalyst 中国科学院长春应用化学研究所 2022-12-30 CN claimed
CN-115028561-A Thiodiglyceramic acid extractant, preparation method and application thereof 江西省科学院应用化学研究所 2022-09-09 CN claimed
CN-114853617-A Extracting agent for extracting and separating neodymium (III), and preparation method and application thereof 山东大学 2022-08-05 CN claimed
WO-2022142566-A1 ALMOND POLYPEPTIDE HAIR CARE NANOMICELLE AND PREPARATION METHOD THEREFOR 华南理工大学 2022-07-07 WO claimed
CN-106602141-B A kind of electrolyte and secondary cell 宁德新能源科技有限公司 2019-01-08 CN claimed
CN-106602141-A Electrolyte and secondary battery 宁德新能源科技有限公司 2017-04-26 CN claimed
US-4323676-A Process for preparing cephalosporins TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-04-06 US claimed
US-4308381-A Cephem compounds TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-12-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240368726-A1 THIODIGLYCOLAMIC ACID EXTRACTANT, AND PREPARATION METHOD AND USE THEREOF GDA, AGL, MGAM TSHR 1287/4885TP53 2066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.