Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 19/20 | 0.38 |
| ▸ | SCN1A | P35498 | 18/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 18/20 | 0.38 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320178 | 0.90 | SCN8A (0.36) | SCN8ASCN1ASCN5ASCN1BNR1I2 | |
| SCHEMBL326999 | 0.88 | SCN8A (0.46) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL36151836 | 0.88 | SCN8A (0.46) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL29607436 | 0.83 | SCN8A (0.35) | SCN8ASCN1ASCN5ASCN1BNR1I2 | |
| SCHEMBL20495895 | 0.80 | SCN8A (0.36) | SCN8ASCN1ASCN5ASCN1BNR1I2 | |
| SCHEMBL19613120 | 0.80 | SCN8A (0.34) | SCN8ASCN1ASCN5ASCN1BCYP2C9 | |
| SCHEMBL321130 | 0.80 | SCN8A (0.35) | SCN8ASCN1ASCN5A | |
| SCHEMBL20574121 | 0.78 | SCN8A (0.48) | SCN8ASCN1ASCN5ASCN1B | |
| SCHEMBL29447370 | 0.78 | SCN8A (0.44) | SCN8ASCN1ASCN5ASCN1BSCN9A | |
| SCHEMBL19627717 | 0.78 | SCN8A (0.44) | SCN8ASCN1ASCN5ASCN1BSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004706-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2012-01-12 | — | — | WO | disclosed |