⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14428593 | 0.83 | — | — | |
| SCHEMBL22015774 | 0.72 | — | — | |
| SCHEMBL2737148 | 0.72 | — | — | |
| SCHEMBL24387726 | 0.69 | — | — | |
| SCHEMBL23205800 | 0.68 | — | — | |
| SCHEMBL28610060 | 0.68 | — | — | |
| SCHEMBL24533113 | 0.68 | — | — | |
| SCHEMBL2081006 | 0.65 | — | — | |
| SCHEMBL73036 | 0.65 | — | — | |
| SCHEMBL22055114 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133303-A1 | COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE, DEGENERATIVE AND METABOLIC DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |
| CN-101622240-B | Fused Substituted Aminopyrrolidine Derivatives | DAIICHI SANKYO CO LTD | 2014-07-23 | — | — | CN | disclosed |
| US-20120040935-A1 | COMPOSITIONS USEFUL AS INHIBITORS OF VOLTAGE-GATED ION CHANNELS | VERTEX PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-7968545-B2 | Compositions useful as inhibitors of voltage-gated ion channels | VERTEX PHARMACEUTICALS INC. (US) | 2011-06-28 | — | — | US | disclosed |
| CN-101622240-A | Fused Substituted Aminopyrrolidine Derivatives | DAIICHI SANKYO CO LTD | 2010-01-06 | — | — | CN | disclosed |