Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.64 |
| ▸ | PPARA | Q07869 | 6/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983405 | 0.94 | PPARG (0.70) | PPARGPPARAPKMRAB9AKDM4E | |
| SCHEMBL2983401 | 0.94 | PPARG (0.70) | PPARGPPARAPKMRAB9AKDM4E | |
| SCHEMBL10151400 | 0.78 | PPARG (0.69) | PPARGPPARARAB9AKDM4EALDH1A1 | |
| SCHEMBL2977109 | 0.77 | PPARG (0.51) | PPARGPPARAPKMRAB9AKDM4E | |
| SCHEMBL10151398 | 0.73 | PPARG (0.47) | PPARGPPARASLC16A3 | |
| SCHEMBL10151761 | 0.72 | PPARG (0.48) | PPARGPPARAALDH1A1MAPTSLC16A3 | |
| SCHEMBL13994559 | 0.71 | PPARG (0.67) | PPARGPPARARAB9ASMN1; SMN2 | |
| SCHEMBL2973717 | 0.70 | PPARG (0.46) | PPARGPPARAMAPT | |
| SCHEMBL2973708 | 0.70 | PPARG (0.46) | PPARGPPARAMAPT | |
| SCHEMBL13042121 | 0.70 | PPARG (0.46) | PPARGPPARAALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1647546-B1 | NOVEL HETEROARYL DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-05-02 | — | — | EP | disclosed |