Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10293237 | 1.00 | FUCA1 (0.43) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| SCHEMBL10151965 | 1.00 | FUCA1 (0.43) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| SCHEMBL10069387 | 1.00 | FUCA1 (0.43) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| SCHEMBL19817617 | 0.98 | EPHX1 (0.42) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| SCHEMBL21232876 | 0.98 | EPHX1 (0.42) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| SCHEMBL22170610 | 0.95 | — | — | |
| Alcohol SCHEMBL14109089 | 0.93 | FUCA1 (0.44) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| Alcohol SCHEMBL14109615 | 0.91 | EPHX1 (0.43) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| Alcohol SCHEMBL14109452 | 0.91 | EPHX1 (0.43) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 | |
| Propanol SCHEMBL14109491 | 0.89 | FUCA1 (0.41) | FUCA1EPHX1TSHRNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955697-B1 | 2-AMINOBENZAMIDE DERIVATIVES AS VANILLOID RECEPTOR 1 (VR1) INHIBITORS USEFUL FOR THE TREATMENT OF PAIN OR BLADDER FUNCTION DISORDER | ASTELLAS PHARMA INC (JP) | 2012-05-02 | — | — | EP | disclosed |