SCHEMBL1015223

SCHEMBL1015223

C=CC(=O)OCCC[SiH2]OCC

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
HPGD P15428 1/20 0.59
ALDH1A1 P00352 5/20 0.55
CYP3A4 P08684 2/20 0.55
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 3/20 0.42
ATM Q13315 1/20 0.40
HCAR2 Q8TDS4 4/20 0.36
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 2/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28175773 0.98 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
Propene SCHEMBL28137991 0.97 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
Hydrochloric Acid SCHEMBL28159246 0.97 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28119923 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28174477 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28107693 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
Trimethylammonium SCHEMBL28223811 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28029882 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27999143 0.95 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL4402758 0.95 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110508222-A Monodisperse core-shell particles and preparation method thereof with mesoporous silicon oxide shell UNIV FUDAN 2019-11-29 CN claimed
CN-110392708-A Adhesive composition based on graft resin 洛德公司 2019-10-29 CN claimed
CN-110218419-A Multipurpose selfreparing autoreaction defense of resistance to impact promotes environment-friendly materials and method 高敏楠 2019-09-10 CN claimed
CN-109843229-A By the pinpoint accuracy drug delivery of dual domain device for eyes 领视药公司 2019-06-04 CN claimed
CN-109820279-A A kind of preparation method of the antifreeze foot warming shoe of waterproof 浙江太极鞋业有限公司 2019-05-31 CN claimed
CN-109793312-A A kind of preparation method of health care playshoes 浙江太极鞋业有限公司 2019-05-24 CN claimed
CN-109790243-A Three block prepolymer and its purposes in silicone hydrogels 庄臣及庄臣视力保护公司 2019-05-21 CN claimed
CN-109749029-A A kind of high molecular polymer and preparation method and application 兰州理工大学 2019-05-14 CN claimed
CN-109730402-A A kind of playshoes and preparation method with double-purpose functional 浙江太极鞋业有限公司 2019-05-10 CN claimed
CN-107304051-B A kind of inorganic nano Porous materials and preparation method thereof 中国科学院化学研究所 2019-03-26 CN claimed
EP-1833905-B1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER MICHELIN & CIE (FR) 2013-08-07 EP claimed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US claimed
US-20120135307-A1 NEGATIVE ACTIVE MATERIAL FOR RECHARGEABLE LITHIUM BATTERY, METHOD OF PRODUCING NEGATIVE ELECTRODE AND RECHARGEABLE LITHIUM BATTERY INCLUDING SAME SAMSUNG SDI., LTD. (KR) 2012-05-31 US claimed
EP-2458661-A1 Negative active material for rechargeable lithium battery, method of producing negative electrode and rechargeable lithium battery including same Samsung SDI Co., Ltd. (KR) 2012-05-30 EP claimed
US-20110021702-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-01-27 US claimed
US-7820771-B2 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S. A. (CH) 2010-10-26 US claimed
EP-1838765-B1 FUNCTIOANALISED POLYVINYLAROMATIC NANOPARTICLES MICHELIN RECH TECH (CH) 2010-08-04 EP claimed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US claimed
US-20090270558-A1 Functionalized Polyvinylaromatic Nanoparticles MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-10-29 US claimed
US-20080132644-A1 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-06-05 US claimed