SCHEMBL10153205

SCHEMBL10153205

CC1(C)c2cc(-c3c4ccccc4c(-c4cccc(F)c4)c4ccccc34)ccc2-c2ccc(-c3c4ccccc4c(-c4c5ccccc5c(-c5cccc(F)c5)c5ccccc45)c4ccccc34)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.48
PGR P06401 6/20 0.40
TAAR1 Q96RJ0 2/20 0.37
ESR2 Q92731 1/20 0.37
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
ADORA2A P29274 1/20 0.35
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
GABRB2 P47870 1/20 0.35
GABRA4 P48169 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153620 0.99 PDK2 (0.50) PDK2PGRTAAR1ESR2PARP10
SCHEMBL10153908 0.98 PDK2 (0.49) PDK2PGRTAAR1ESR2PARP10
SCHEMBL10153582 0.97 PDK2 (0.51) PDK2PGRTAAR1ESR2PARP10
SCHEMBL10153236 0.96 PDK2 (0.51) PDK2PGRTAAR1ESR2
SCHEMBL14600377 0.96 PDK2 (0.51) PDK2PGRTAAR1ESR2
SCHEMBL10153964 0.95 PDK2 (0.53) PDK2PGRTAAR1ESR2PARP10
SCHEMBL10153559 0.95 PDK2 (0.53) PDK2PGRTAAR1ESR2PARP10
SCHEMBL10153426 0.94 PDK2 (0.52) PDK2PGRTAAR1ESR2
SCHEMBL10153393 0.94 PDK2 (0.52) PDK2PGRTAAR1ESR2
SCHEMBL10153623 0.93 PDK2 (0.54) PDK2PGRTAAR1ESR2PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed