SCHEMBL10153289

SCHEMBL10153289

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(-c5c6ccccc6c(-c6ccc(F)cc6)c6ccccc56)ccc3-4)cc21

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 16/20 0.49
ACHE P22303 1/20 0.39
PGR P06401 1/20 0.39
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153428 1.00 PDK2 (0.49) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL10153214 0.99 PDK2 (0.48) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL10153179 0.99 PDK2 (0.51) PDK2ACHEPGR
SCHEMBL10153963 0.99 PDK2 (0.48) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL10153345 0.99 PDK2 (0.47) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL10153152 0.99 PDK2 (0.47) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL14600374 0.97 PDK2 (0.46) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL10153231 0.97 PDK2 (0.46) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL13488114 0.96 PDK2 (0.46) PDK2ACHEPGRKDM4ECYP1A2
SCHEMBL14600413 0.96 PDK2 (0.46) PDK2ACHEPGRKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed
US-7166240-B2 Hydrocarbon compounds, materials for organic electroluminescent elements and organic electroluminescent elements MITSUI CHEMICALS, INC. (JP) 2007-01-23 US disclosed