SCHEMBL10153479

SCHEMBL10153479

CCCCCCCCCCOc1ccc(C(=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.63
TSHR P16473 1/20 0.63
PLA2G4B P0C869 6/20 0.61
NR5A1 Q13285 1/20 0.61
RARB P10826 3/20 0.58
NPC1 O15118 1/20 0.58
LMNA P02545 1/20 0.58
GAA P10253 1/20 0.58
MAPT P10636 1/20 0.58
ALOX15 P16050 1/20 0.58
RAB9A P51151 1/20 0.58
HSD17B10 Q99714 1/20 0.58
PLA2G4A P47712 1/20 0.55
SLC2A1 P11166 2/20 0.54
LTA4H P09960 1/20 0.53
THRA P10827 1/20 0.52
THRB P10828 1/20 0.52
PLK1 P53350 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862518 1.00 TP53 (0.63) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL13991627 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL22207170 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL7761726 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL21167283 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL14583368 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL22207529 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL22207285 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL22207172 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB
SCHEMBL12122194 0.89 NR5A1 (0.68) TP53TSHRPLA2G4BNR5A1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed