SCHEMBL10153565

SCHEMBL10153565

CCCCCCCCOc1cc(/C=C/c2cc(C)c(/C=C/c3cc(C)c(C)cc3OCCCCCCCC)cc2OC)c(C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 4/20 0.36
ESR1 P03372 2/20 0.36
THRB P10828 4/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
THRA P10827 3/20 0.34
HMGCR P04035 1/20 0.34
CYP3A4 P08684 1/20 0.34
PDE4B Q07343 1/20 0.34
DPP4 P27487 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33
S1PR5 Q9H228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10153468 0.96 SMPD1 (0.37) SMPD1ESR1THRBMEN1KMT2A
SCHEMBL10153459 0.95 ESR1 (0.39) ESR1THRBMEN1KMT2ATHRA
SCHEMBL10153467 0.95 ESR1 (0.39) ESR1THRBMEN1KMT2ATHRA
SCHEMBL862834 0.93 SMPD1 (0.40) SMPD1ESR1THRBTHRAHMGCR
SCHEMBL862614 0.90 ESR1 (0.42) ESR1THRBMEN1KMT2ATHRA
SCHEMBL862619 0.89 SMPD1 (0.41) SMPD1ESR1THRBTHRAPDE4B
SCHEMBL10153553 0.88 ESR1 (0.38) SMPD1ESR1THRBTHRAS1PR5
SCHEMBL862517 0.87 ESR1 (0.43) ESR1THRBMEN1KMT2ATHRA
SCHEMBL12252238 0.87 ESR1 (0.43) ESR1THRBMEN1KMT2ATHRA
SCHEMBL10153560 0.86 ESR1 (0.34) ESR1THRBMEN1KMT2ATHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120008068-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-12 US disclosed