SCHEMBL10154004

SCHEMBL10154004

CCCCOc1ccc(-c2c3ccccc3c(-c3c4ccccc4c(-c4ccc5c(c4)C(C)(C)c4cc(-c6ccc7c(c6)C(C)(C)c6ccccc6-7)ccc4-5)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.46
CYP2D6 P10635 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP19A1 P11511 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
CTSV O60911 1/20 0.40
CTSL P07711 1/20 0.40
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLA2G2A P14555 1/20 0.38
LTA4H P09960 2/20 0.38
ALK Q9UM73 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14600495 0.99 PDK2 (0.45) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL14600428 0.99 PDK2 (0.45) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL14600360 0.98 PDK2 (0.46) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL14600457 0.98 PDK2 (0.46) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL14600434 0.96 PDK2 (0.46) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL14600394 0.96 PDK2 (0.46) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL14600493 0.95 PDK2 (0.46) PDK2CYP1A2CYP2C19MAPTKDM4E
SCHEMBL14600423 0.95 PDK2 (0.46) PDK2CYP1A2CYP2C19MAPTKDM4E
SCHEMBL14600489 0.95 CYP2D6 (0.43) PDK2CYP2D6CYP1A2CYP19A1CYP2C9
SCHEMBL10153258 0.94 PDK2 (0.46) PDK2CYP1A2CYP2C19MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221434-B1 HYDROCARBON COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUI CHEMICALS INC (JP) 2012-06-27 EP disclosed