Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 6/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154324 | 0.94 | CYP3A4 (0.40) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL24119305 | 0.91 | CYP3A4 (0.38) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL18636591 | 0.88 | CYP3A4 (0.47) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL20878372 | 0.88 | CYP3A4 (0.47) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL19223082 | 0.88 | CYP3A4 (0.47) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL17712516 | 0.86 | CYP3A4 (0.48) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL17712518 | 0.86 | CYP3A4 (0.48) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL807683 | 0.86 | CYP3A4 (0.48) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL24057879 | 0.86 | CYP3A4 (0.48) | CYP3A4CYP2C9BTN3A1RIPK1 | |
| SCHEMBL18293558 | 0.84 | CYP3A4 (0.45) | CYP3A4CYP2C9BTN3A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012776-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2012-01-26 | — | — | WO | disclosed |