SCHEMBL10155595

SCHEMBL10155595

CC(C)C1(C(C)C)CS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12521914 0.67
SCHEMBL12026386 0.64
SCHEMBL9210760 0.59
SCHEMBL9880277 0.59
SCHEMBL9882952 0.57
SCHEMBL11823443 0.50
SCHEMBL27604043 0.46
SCHEMBL504428 0.45
Hydrochloric Acid SCHEMBL8039204 0.42
Hydrochloric Acid SCHEMBL22492262 0.42

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9656974-B2 Oxazine derivatives SHIONOGI & CO., LTD. (JP) 2017-05-23 US disclosed
US-20160159757-A1 OXAZINE DERIVATIVES SHIONOGI & CO (JP) 2016-06-09 US disclosed
US-9290466-B2 Oxazine derivatives SHIONOGI & CO., LTD. (JP) 2016-03-22 US disclosed
US-20150166491-A1 OXAZINE DERIVATIVES SHIONOGI & CO (JP) 2015-06-18 US disclosed
US-9018219-B2 Fused aminodihydropyrimidine derivative SHIONOGI & CO., LTD. (JP) 2015-04-28 US disclosed
US-8999980-B2 Oxazine derivatives SHIONOGI & CO., LTD. (JP) 2015-04-07 US disclosed
US-8927721-B2 Naphthyridine derivative SHIONOGI & CO., LTD. (JP) 2015-01-06 US disclosed
US-20140235626-A1 PYRIDINE DERIVATIVES AND A PHARMACEUTICAL COMPOSITION FOR INHIBITING BACE1 CONTAINING THEM SHIONOGI & CO., LTD. (JP) 2014-08-21 US disclosed
US-20130217705-A1 NAPHTHYRIDINE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2013-08-22 US disclosed
US-20130210839-A1 FUSED AMINODIHYDROPYRIMIDINE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2013-08-15 US disclosed
US-20120258961-A1 4-AMINO-1,3-THIAZINE OR OXAZINE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2012-10-11 US disclosed
US-20120245155-A1 FUSED HETEROCYCLIC COMPOUND HAVING AMINO GROUP SHIONOGI & CO., LTD. (JP) 2012-09-27 US disclosed
US-20120238557-A1 AMINOTHIAZINE OR AMINOOXAZINE DERIVATIVE HAVING AMINO LINKER SHIONOGI & CO., LTD. (JP) 2012-09-20 US disclosed
US-20120015961-A1 ISOTHIOUREA DERIVATIVES OR ISOUREA DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY SHIONOGI & CO., LTD. (JP) 2012-01-19 US disclosed