SCHEMBL10156047

SCHEMBL10156047

CN1C(C)(C)CC(N2CN3C(=O)N4CN(C5CC(C)(C)N(C)C(C)(C)C5)CN5C(=O)N(C2)C3C45)CC1(C)C

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.37
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14299876 0.92 MAPK1 (0.33) MAPK1
SCHEMBL13290098 0.91 MAPK1 (0.51) MAPK1LMNA
SCHEMBL12723445 0.89 MAPK1 (0.32) MAPK1
SCHEMBL13871885 0.89 MAPK1 (0.32) MAPK1
SCHEMBL13889856 0.83
SCHEMBL13876987 0.81
SCHEMBL13148271 0.80 MAPK1 (0.38) MAPK1LMNA
SCHEMBL310962 0.79 MAPK1 (0.59) MAPK1LMNA
SCHEMBL11322550 0.77 MAPK1 (0.34) MAPK1
SCHEMBL11324452 0.76 MAPK1 (0.33) MAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461235-B2 Use of polymer powder containing UV absorber for the stabilisation of polymers against the effects of UV radiation BASF SE (DE) 2013-06-11 US disclosed
US-8461235-B2 Use of polymer powder containing UV absorber for the stabilisation of polymers against the effects of UV radiation BASF SE (DE) 2013-06-11 US disclosed
US-8277695-B2 Reversibly thermochromic compositions BASF SE (DE) 2012-10-02 US disclosed
US-8262945-B2 Stabilization of photochromic systems BASF SE (DE) 2012-09-11 US disclosed
US-8119778-B2 Reversibly thermochromic compositions BASF SE (DE) 2012-02-21 US disclosed
US-20110180767-A1 Reversibly thermochromic compositions CIBA CORPORATION 2011-07-28 US disclosed
US-20110092632-A1 POROUS INORGANIC MATERIALS CONTAINING POLYMER ADDITIVES BRAND FABIEN JEAN 2011-04-21 US disclosed
US-7820744-B2 Stabilizer mixtures CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-26 US disclosed
US-7786199-B2 Flame-retardants CIBA SPECIALTY CHEMICALS CORP. (US) 2010-08-31 US disclosed
US-20100190929-A1 USE OF POLYMER POWDER CONTAINING UV ABSORBER FOR THE STABILISATION OF POLYMERS AGAINST THE EFFECTS OF UV RADIATION BASF AKTIENGESELLSCHAFT (DE) 2010-07-29 US disclosed
US-20090105379-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-23 US disclosed
US-20090093572-A1 Stabilizer mixtures GUGUMUS FRANCOIS 2009-04-09 US disclosed
US-20080269383-A1 Flame-Retardants CIBA SPECIALTY CEMICALS HOLDING INC. (CH) 2008-10-30 US disclosed
US-20080220031-A1 Dermocosmetic Preparations BASF AKTIENGESELLSCHAFT (DE) 2008-09-11 US disclosed
US-20080220031-A1 Dermocosmetic Preparations BASF AKTIENGESELLSCHAFT (DE) 2008-09-11 US disclosed
US-20080058459-A1 Porous Inorganic Materials Containing Polymer Additives CIBA CORP. 2008-03-06 US disclosed
US-20080027160-A1 Weatherability of flame retardant polyolefin ZINGG JURG 2008-01-31 US disclosed
US-20070135537-A1 Agricultural articles BONORA MICHAEL 2007-06-14 US disclosed
US-20070064195-A1 Stabilization of photochromic systems CIBA CORPORATION 2007-03-22 US disclosed
US-7169835-B2 Stabilizer mixture CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110180767-A1 Reversibly thermochromic compositions C1R, C3AR1, C9 MAPK1 1896/4885LMNA 2222/4885
US-20080220031-A1 Dermocosmetic Preparations C3AR1, C1S, C1R MAPK1 2373/4885LMNA 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.