SCHEMBL10156243

SCHEMBL10156243

Nc1ncc(-c2ccc(C3(c4noc(-c5cc([N+](=O)O)n[nH]5)n4)CCC3)cn2)cn1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL877543 0.92 ALOX5AP (0.76) ALOX5AP
SCHEMBL881841 0.85 ALOX5AP (0.83) ALOX5AP
SCHEMBL876443 0.81 ALOX5AP (0.84) ALOX5AP
SCHEMBL881819 0.78 ALOX5AP (1.00) ALOX5AP
SCHEMBL881624 0.77 ALOX5AP (0.75) ALOX5AP
SCHEMBL881893 0.77 ALOX5AP (0.81) ALOX5AP
SCHEMBL881657 0.77 ALOX5AP (0.71) ALOX5AP
SCHEMBL881739 0.76 ALOX5AP (1.00) ALOX5AP
SCHEMBL881744 0.76 ALOX5AP (1.00) ALOX5AP
SCHEMBL882004 0.76 ALOX5AP (1.00) ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012040139-A1 OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-03-29 WO disclosed