Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015308 | 0.91 | S1PR1 (0.57) | S1PR1 | |
| SCHEMBL1016210 | 0.89 | S1PR1 (0.55) | S1PR1 | |
| SCHEMBL1015629 | 0.89 | S1PR1 (0.54) | S1PR1 | |
| SCHEMBL1016062 | 0.88 | S1PR1 (0.58) | S1PR1 | |
| SCHEMBL1015466 | 0.87 | S1PR1 (0.47) | S1PR1 | |
| SCHEMBL1014881 | 0.86 | S1PR1 (0.42) | S1PR1 | |
| SCHEMBL11983625 | 0.82 | S1PR1 (0.48) | S1PR1 | |
| Hydrochloric Acid SCHEMBL1014090 | 0.82 | S1PR1 (0.48) | S1PR1 | |
| SCHEMBL1015139 | 0.82 | S1PR1 (0.66) | S1PR1 | |
| SCHEMBL1014774 | 0.81 | S1PR1 (0.56) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271643-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009133136-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |