SCHEMBL10156531

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10154813	0.90	BACE1 (0.61)	NPC1RAB9ABACE1RPS6KA2KDM4E
	SCHEMBL10155909	0.81	BACE1 (0.61)	NPC1RAB9ABACE1
	SCHEMBL10156455	0.80	BACE1 (0.61)	NPC1RAB9ABACE1KDM4ESMN1; SMN2
	SCHEMBL10156245	0.80	NPC1 (0.55)	NPC1RAB9ABACE1KDM4EALDH1A1
	SCHEMBL10156415	0.79	BACE1 (0.58)	NPC1RAB9ABACE1KDM4E
	SCHEMBL10157435	0.77	BACE1 (0.59)	BACE1
	SCHEMBL10155339	0.77	BACE1 (0.55)	BACE1
	SCHEMBL10156981	0.77	BACE1 (0.55)	BACE1ALDH1A1TP53HSD17B10
	SCHEMBL15975725	0.77	BACE1 (0.61)	BACE1
	SCHEMBL10155161	0.76	BACE1 (0.55)	BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.