⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062895 | 0.72 | — | — | |
| SCHEMBL15935826 | 0.72 | — | — | |
| SCHEMBL587919 | 0.72 | — | — | |
| SCHEMBL6851278 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL11774648 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL11246727 | 0.69 | — | — | |
| SCHEMBL9281937 | 0.69 | — | — | |
| SCHEMBL11841007 | 0.69 | — | — | |
| SCHEMBL9591980 | 0.69 | — | — | |
| SCHEMBL19018659 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927513-B2 | 5′ phosphate mimics | ALNYLAM PHARMACEUTICALS, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20120157511-A1 | 5' PHOSPHATE MIMICS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-21 | — | — | US | disclosed |