Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015455 | 0.99 | CNR1 (0.55) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1015929 | 0.98 | CNR1 (0.54) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1015926 | 0.90 | CNR1 (0.53) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1015061 | 0.90 | CNR1 (0.53) | CNR1POLBG6PDMAPTTP53 | |
| SCHEMBL1016298 | 0.85 | SERPINE1 (0.54) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1014958 | 0.84 | SERPINE1 (0.55) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1015829 | 0.84 | CNR1 (0.53) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1016300 | 0.83 | SERPINE1 (0.54) | CNR1POLBG6PDSERPINE1MAPT | |
| SCHEMBL1015605 | 0.83 | SERPINE1 (0.56) | POLBG6PDSERPINE1MAPTGRIK1 | |
| SCHEMBL1015361 | 0.83 | CNR1 (0.54) | CNR1POLBG6PDSERPINE1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990057-B1 | PAI-1 INHIBITOR FOR USE IN ENHANCING THE ANTITUMOR EFFECT OF AN ANTITUMOR AGENT IN A PATIENT | RENASCIENCE CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |
| EP-2272822-A1 | INHIBITOR OF PLASMINOGEN ACTIVATOR INHIBITOR-1 | Renascience CO., LTD. (JP) | 2011-01-12 | — | — | EP | disclosed |