Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1016006 | 1.00 | EGFR (0.69) | EGFRMKNK1 | |
| SCHEMBL1015462 | 0.93 | EGFR (0.60) | EGFRMKNK1 | |
| SCHEMBL1015463 | 0.93 | EGFR (0.60) | EGFRMKNK1 | |
| SCHEMBL1015727 | 0.93 | EGFR (0.67) | EGFRMKNK1 | |
| SCHEMBL1015726 | 0.93 | EGFR (0.67) | EGFRMKNK1 | |
| SCHEMBL940104 | 0.92 | EGFR (0.70) | EGFRMKNK1 | |
| SCHEMBL940102 | 0.92 | EGFR (0.70) | EGFRMKNK1 | |
| SCHEMBL1017392 | 0.91 | EGFR (0.60) | EGFRMKNK1 | |
| SCHEMBL1017393 | 0.91 | EGFR (0.60) | EGFRMKNK1 | |
| SCHEMBL1019667 | 0.91 | EGFR (0.62) | EGFRMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001890-B1 | TETRAHYDROPYRIDOTHIENOPYRIMIDINE COMPOUNDS AND USE FOR THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | BAYER SCHERING PHARMA AG (DE) | 2011-01-12 | — | — | EP | disclosed |