Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10132281 | 0.81 | MAPK1 (0.51) | MAPK1DRD2DRD4 | |
| SCHEMBL15859012 | 0.80 | MAPK1 (0.50) | MAPK1DRD2DRD4 | |
| SCHEMBL18948460 | 0.80 | MAPK1 (0.50) | MAPK1DRD2DRD4 | |
| SCHEMBL10162449 | 0.80 | GAA (0.56) | DRD2 | |
| SCHEMBL16549649 | 0.80 | MAPK1 (0.69) | MAPK1DRD2DRD4 | |
| SCHEMBL15787899 | 0.78 | MAPK1 (0.48) | MAPK1DRD2DRD4 | |
| SCHEMBL12126936 | 0.78 | KDM4E (0.52) | MAPK1DRD2DRD3 | |
| SCHEMBL10162628 | 0.77 | KMT2A (0.46) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL10162738 | 0.77 | KMT2A (0.46) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL10161180 | 0.76 | ESR1 (0.45) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | PANACEA BIOTEC LTD. (IN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165320-A1 | NOVEL AZABICYCLOHEXANES | CYP3A43, UGT1A1, CYP3A4 | MAPK1 3137/4885DRD2 834/4885DRD4 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.