SCHEMBL1016633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1020117	0.92	GRM5 (0.45)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1017066	0.92	DPP4 (0.40)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1017805	0.92	DPP4 (0.42)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1017927	0.90	DPP4 (0.47)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1015270	0.90	DPP4 (0.41)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL12953685	0.90	DPP4 (0.41)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1014681	0.89	GRM5 (0.46)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1017197	0.88	DPP4 (0.40)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1603657	0.88	HRH3 (0.45)	DPP4DPP8DPP7DPP9TLR9
	SCHEMBL1017188	0.88	NPC1 (0.42)	DPP4DPP8DPP7DPP9TLR9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.