Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.64 |
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327702 | 0.91 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL9951268 | 0.91 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL9951471 | 0.86 | BCL2 (0.84) | BCL2BCL2L1 | |
| SCHEMBL15327644 | 0.86 | BCL2 (0.84) | BCL2BCL2L1 | |
| SCHEMBL9951703 | 0.82 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL9951687 | 0.82 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL10166474 | 0.81 | BCL2 (0.64) | BCL2BCL2L1 | |
| SCHEMBL9951607 | 0.81 | BCL2 (0.75) | BCL2BCL2L1 | |
| SCHEMBL9951601 | 0.78 | BCL2 (0.82) | BCL2BCL2L1 | |
| SCHEMBL1497217 | 0.78 | BCL2 (1.00) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165298-A1 | SULFONAMIDE COMPOUNDS | NOVARTIS AG (CH) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165298-A1 | SULFONAMIDE COMPOUNDS | BCLAF1, BCL2L11, BCL2 | BCL2 3/4885BCL2L1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.