⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252302 | 0.93 | CYP1A2 (0.59) | — | |
| SCHEMBL25823863 | 0.91 | CYP1A2 (0.57) | — | |
| SCHEMBL8233910 | 0.91 | CYP1A2 (0.57) | — | |
| SCHEMBL12824155 | 0.91 | CYP1A2 (0.57) | — | |
| SCHEMBL11907833 | 0.85 | — | — | |
| SCHEMBL8570508 | 0.85 | CYP1A2 (0.73) | — | |
| SCHEMBL50610 | 0.85 | CYP1A2 (0.73) | — | |
| SCHEMBL1331978 | 0.85 | CYP1A2 (0.73) | — | |
| SCHEMBL50734 | 0.85 | CYP1A2 (0.73) | — | |
| SCHEMBL1483107 | 0.82 | CYP1A2 (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324410-B2 | Modified drugs for use in liposomal nanoparticles | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-12-04 | — | — | US | disclosed |
| US-20120237591-A1 | MODIFIED DRUGS FOR USE IN LIPOSOMAL NANOPARTICLES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-09-20 | — | — | US | disclosed |
| EP-1534680-B1 | PRENYLATION INHIBITORS AND METHODS OF THEIR SYNTHESIS AND USE | PHARMACO INVESTMENTS INC (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-1657235-B1 | Phenethanolamine-derived haptens, immunogens and conjugates comprising them and antibodies recognising said immunogenes and conjugates | RANDOX LAB LTD (GB) | 2011-09-21 | — | — | EP | disclosed |
| US-20110165225-A1 | Modified Drugs for Use in Liposomal Nanoparticles | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-07-07 | — | — | US | disclosed |
| WO-2011001052-A1 | NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-06 | — | — | WO | disclosed |
| EP-2236489-A1 | METHOD FOR PRODUCTION OF (2E,6Z,8E)-N-ISOBUTYL-2,6,8-DECATRIENAMIDE (SPILANTHOL), AND FOODS, BEVERAGES, COSMETICS AND PHARMACEUTICAL PREPARATIONS EACH COMPRISING THE COMPOUND | Takasago International Corporation (JP) | 2010-10-06 | — | — | EP | disclosed |
| US-20100105144-A1 | ONIUM SALTS AND USE THEREOF FOR DETECTING AND ASSAYING METALS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-04-29 | — | — | US | disclosed |
| WO-2010006172-A2 | 2-METHYLENE-20(21)-DEHYDRO-19-NOR-VITAMIN D ANALOGS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-14 | — | — | WO | disclosed |
| WO-2010006162-A2 | 2-METHYLENE-(20E)-20(22)-DEHYDRO-19-NOR-VITAMIN D ANALOGS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-14 | — | — | WO | disclosed |
| EP-2112138-A1 | Onium salts and their use for detecting and dosing metals | Commissariat a L'Energie Atomique (FR) | 2009-10-28 | — | — | EP | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008005268-A1 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF | SCHERING CORPORATION (US) | 2008-01-10 | — | — | WO | disclosed |
| EP-1249450-B1 | BENZIMIDAZOLE DERIVATIVES AS HUMAN CHYMASE INHIBITORS | TEIJIN PHARMA LTD (JP) | 2007-10-10 | — | — | EP | disclosed |