SCHEMBL1016806

SCHEMBL1016806

Nc1ccc(Oc2ccccc2-c2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 1.00
NCOA3 Q9Y6Q9 1/20 1.00
MAOA P21397 1/20 0.57
PTGS2 P35354 1/20 0.50
ALDH1A1 P00352 4/20 0.48
CYP3A4 P08684 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TSHR P16473 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
NLRP3 Q96P20 1/20 0.47
BRD4 O60885 3/20 0.47
HSD17B10 Q99714 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
AR P10275 1/20 0.46
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351899 1.00 NCOA1 (1.00) NCOA1NCOA3MAOAPTGS2ALDH1A1
SCHEMBL5745005 0.94 NCOA1 (0.89) NCOA1NCOA3MAOAPTGS2ALDH1A1
SCHEMBL9360097 0.92 NCOA1 (0.86) NCOA1NCOA3MAOAPTGS2ALDH1A1
SCHEMBL3786953 0.92 NCOA1 (0.86) NCOA1NCOA3MAOAPTGS2ALDH1A1
SCHEMBL1098553 0.89 NCOA1 (0.80) NCOA1NCOA3MAOAPTGS2ALDH1A1
SCHEMBL29992912 0.88 NCOA1 (0.78) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL1143083 0.88 NCOA1 (0.78) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL25135230 0.87 NCOA1 (0.77) NCOA1NCOA3MAOAPTGS2ALDH1A1
SCHEMBL6909243 0.87 NCOA1 (0.77) NCOA1NCOA3MAOAALDH1A1CYP3A4
SCHEMBL2463739 0.87 NCOA1 (0.76) NCOA1NCOA3MAOAPTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2402 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115723393-B Support body and application thereof 杭州福斯特应用材料股份有限公司 2024-07-16 CN claimed
CN-118344646-A Preparation method of shape memory fluorine-containing block polyimide aerogel with flexibility 江南大学 2024-07-16 CN claimed
CN-118307778-A Extrusion type polyimide material, preparation method and application thereof 上海三普水相材料科技有限公司 2024-07-09 CN claimed
CN-118290794-A Coating type modified polyimide film with carrier film and preparation method thereof 昆山雅森电子材料科技有限公司 2024-07-05 CN claimed
CN-115873249-B Plasma-treated fiber-reinforced polyimide material and preparation method thereof 黄山金石木塑料科技有限公司 2024-06-28 CN claimed
CN-118255988-A Polyimide molded article and method for producing same 聚酰亚胺先端材料有限公司 2024-06-28 CN claimed
CN-118240374-A Resin composition and application thereof 广东生益科技股份有限公司 2024-06-25 CN claimed
CN-116410594-B Resin composition, prepreg and metal foil-clad laminate 广东生益科技股份有限公司 2024-06-14 CN claimed
CN-118165354-A Preparation method of 4D-printable multi-shape memory polyimide composite aerogel material 江南大学 2024-06-11 CN claimed
CN-118146505-A Polymer and thermal interface material 财团法人工业技术研究院 2024-06-07 CN claimed
WO-2007091807-A1 COPPER CLAD LAMINATE FOR CHIP ON FILM LG CHEM, LTD. (KR) 2007-08-16 WO claimed
EP-1368411-A1 PHOTOACTIVE POLYMER Rolic AG (CH) 2003-12-10 EP claimed
WO-2002062873-A9 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-10-03 WO claimed
WO-2002062873-A1 PHOTOACTIVE POLYMER ROLIC AG (CH) 2002-08-15 WO claimed
EP-0716113-B1 Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof TOHO RAYON KK (JP) 2000-01-19 EP claimed
EP-0448252-B1 Polyimide copolymers containing 4-4'-bis(aminophenoxy)biphenyl and siloxane diamine moieties AMOCO CORP (US) 1994-11-30 EP claimed
EP-0603339-A1 POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES AMOCO CORPORATION (US) 1994-06-29 EP claimed
US-5246784-A ULTRATHIN THERMOSTABLE BISMALEIMIDE FILMS AND PRODUCTION THEREOF BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US claimed
WO-1993006151-A1 POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES AMOCO CORPORATION (US) 1993-04-01 WO claimed
EP-0122060-A2 Melt-fusible polyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-17 EP claimed